The animals in Aunt Lucy’s zoo are getting sick and causing zoo attendance to decline. Unless she can turn things around, Aunt Lucy will lose her zoo to a local landowner who wants to build a mini-golf course. To help save the zoo and its inhabitants, players will use the Wii Remote to feed, treat and soothe 48 different animals from all over the world – from gorillas to monitor lizards to dolphins – including seven not featured in the companion DS game. Medical mini-games let players eliminate parasites, extract rotten teeth, battle microscopic germs and much more. Soothing and feeding each animal while following up on post surgical patients in their enclosures is as important as precise operations, since happy, healthy animals increase the Zoo Rating which in turn affects the number of visitors patronizing the zoo. Zoo Hospital also enables up to 2 friends to treat animals together in cooperative multi-player mode.